ATIM-37. PHASE II, OPEN-LABEL, SINGLE ARM, MULTICENTER STUDY OF AVELUMAB WITH HYPOFRACTIONATED RADIATION (HFRT) FOR ADULT PATIENTS WITH SECONDARILY TRANSFORMED IDH-MUTANT GLIOBLASTOMA (GBM)

BACKGROUND: There is no effective therapy for patients (pts) with IDH-mutant gliomas that progress after RT and chemotherapy. At time of progression, these tumors have often transformed to glioblastoma (GBM) and have increased numbers of somatic mutations, i.e. have a “hypermutator phenotype”. We hy...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kurz, Sylvia, Silverman, Joshua S, Hochman, Tsivia, Nayak, Lakshmi, Arrillaga-Romany, Isabel, Lee, Eudocia, Patel, Amie, Delara, Malcolm, Hsu, Fraustina, Imtiaz, Tooba, Magnelli, Lori, Taylor, Jennie, Cloughesy, Timothy, Sulman, Erik, Golfinos, John, Zagzag, David, Snuderl, Matija, Goldberg, Judith D, Chi, Andrew S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Adult Clinical Trials–Immunologic
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847193/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.036
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados