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ATIM-37. PHASE II, OPEN-LABEL, SINGLE ARM, MULTICENTER STUDY OF AVELUMAB WITH HYPOFRACTIONATED RADIATION (HFRT) FOR ADULT PATIENTS WITH SECONDARILY TRANSFORMED IDH-MUTANT GLIOBLASTOMA (GBM)

BACKGROUND: There is no effective therapy for patients (pts) with IDH-mutant gliomas that progress after RT and chemotherapy. At time of progression, these tumors have often transformed to glioblastoma (GBM) and have increased numbers of somatic mutations, i.e. have a “hypermutator phenotype”. We hy...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Kurz, Sylvia, Silverman, Joshua S, Hochman, Tsivia, Nayak, Lakshmi, Arrillaga-Romany, Isabel, Lee, Eudocia, Patel, Amie, Delara, Malcolm, Hsu, Fraustina, Imtiaz, Tooba, Magnelli, Lori, Taylor, Jennie, Cloughesy, Timothy, Sulman, Erik, Golfinos, John, Zagzag, David, Snuderl, Matija, Goldberg, Judith D, Chi, Andrew S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847193/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.036
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