RDNA-05. RADIOTHERAPY PROMOTES ONCOPROGRESSIVE CROSSTALK BETWEEN GLIOBLASTOMA TUMOR CELLS AND M2 MACROPHAGES VIA THE NLRP3 INFLAMMASOME PATHWAY

PURPOSE: Radiotherapy (RT) is an essential component in the adjuvant treatment of glioblastoma (GBM); however, despite an initial benefit in tumor control, recurrence is nearly universal. The inflammasome is a multimeric cytosolic complex that has been shown to be activated in immune cells following...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: An, Shejuan, Rooney, Michael K, Miska, Jason, Lee Chang, Catalina, Zhang, Peng, Han, Yu, Lopez-Rosas, Aurora, Lesniak, Maciej S, Sachdev, Sean
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
Onderwerpen:
Radiation Biology and DNA Repair
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847174/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.865
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