IMMU-07. CELLULAR IMMUNOTHERAPY TO OVERCOME TEMOZOLOMIDE INDUCED T CELL EXHAUSTION IN GLIOBLASTOMA

INTRODUCTION: We have previously demonstrated that standard dose (SD) temozolomide results in T cell exhaustion in glioblastoma. In this study, we hypothesized that cellular immunotherapies will prevent T cell exhaustion. We tested temozolomide treatment with adoptive T cell transfer alone, dendriti...

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Publicat a:Neuro Oncol
Autors principals: Karachi, Aida, Dastmalchi, Farhad, O’Malley, Ashley, Saia, Megan, Mitchell, Duane, Rahman, Maryam
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847072/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.501
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