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PATH-48. THE DNA METHYLATION LANDSCAPE OF CORE AND PERIPHERAL DIFFUSE GLIOMA REGIONS SHOWS LITTLE SPATIAL SUBTYPE HETEROGENEITY AFTER CONSIDERING TUMOR PURITY

While diffuse gliomas are notorious for their histopathological, genetic and transcriptional spatial heterogeneity, little is known about their epigenetic spatial heterogeneity. The result of spatial (epi)genetic analysis is strongly influenced by the proportion of cancer cells in a sample, so calle...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Verburg, Niels, Barthel, Floris, Anderson, Kevin, Koopman, Thomas, Yaqub, Maqsood, Hoekstra, Otto, Lammertsma, Adriaan, Barkhof, Frederik, Pouwels, Petra, C Reijneveld, Jaap, Heijmans, Jan, Rozemuller, Annemieke, Costello, Joseph, Taylor, Michael, Vandertop, William, Boellaard, Ronald, Johnson, Kevin C, Wesseling, Pieter, de Witt Hamer, Philip, Verhaak, Roel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847013/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.644
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