PATH-48. THE DNA METHYLATION LANDSCAPE OF CORE AND PERIPHERAL DIFFUSE GLIOMA REGIONS SHOWS LITTLE SPATIAL SUBTYPE HETEROGENEITY AFTER CONSIDERING TUMOR PURITY

While diffuse gliomas are notorious for their histopathological, genetic and transcriptional spatial heterogeneity, little is known about their epigenetic spatial heterogeneity. The result of spatial (epi)genetic analysis is strongly influenced by the proportion of cancer cells in a sample, so calle...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Verburg, Niels, Barthel, Floris, Anderson, Kevin, Koopman, Thomas, Yaqub, Maqsood, Hoekstra, Otto, Lammertsma, Adriaan, Barkhof, Frederik, Pouwels, Petra, C Reijneveld, Jaap, Heijmans, Jan, Rozemuller, Annemieke, Costello, Joseph, Taylor, Michael, Vandertop, William, Boellaard, Ronald, Johnson, Kevin C, Wesseling, Pieter, de Witt Hamer, Philip, Verhaak, Roel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Molecular Pathology and Classification - Adult and Pediatric
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847013/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.644
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