EXTH-68. INTRANASAL DELIVERY OF DRUG-LOADED LIPOSOMES SENSITIZES TUMORS TO IRRADIATION IN SYNGENEIC MODEL OF GLIOMA.

Tumor-associated myeloid cells (TAMCs) are appealing therapeutic target in glioblastoma (GBM) due to their immunosuppressive function and robust presence in the tumor tissue. We designed a lipid nanoparticle (LNP) modified with anti-PD-L1 antibody (αPD-L1) for targeted delivery to PD-L1 expressing c...

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Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Zhang, Peng, Zannikou, Markella, Lesniak, Maciej S, Balyasnikova, Irina
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846930/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.398
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