TMOD-21. TARGETING ANAPLASTIC MENINGIOMA WITH PANOBINOSTAT IN PATIENT-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS DERIVED FROM A MATCHING PAIR OF PRIMARY AND RECURRENT TUMORS

BACKGROUND: Meningioma is the most common brain tumor in adults. Despite the overall benign nature of meningioma, skull base tumors can be difficult to completely resect while others exhibit progression and aggressive profiles. The lack of clinically relevant animal models is blocking the developmen...

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Publicado en:Neuro Oncol
Autores principales: Zhang, Huiyuan, Qi, Lin, Du, Yuchen, Braun, Frank, Kogiso, Mari, Huang, Lei, Klisch, Tiemo, Zhao, Yanling, Guo, Lei, Li, Can, Zhao, Sibo, Lindsay, Holly B, Injac, Sarah, Baxter, Patricia, Su, Jack, Stephan, Clifford, Keller, Charles, Yang, Jianhua, Li, Xiao-Nan, Patel, Akash
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Tumor Models
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846839/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1120
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