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IMMU-27. IMMUNE CHECKPOINT BLOCKADE OF EX VIVO EXPANDED T CELLS FOR USE IN ADOPTIVE CELLULAR THERAPY (ACT) FOR GLIOBLASTOMA

BACKGROUND: Despite aggressive treatments, GBM continues to have unacceptably high mortality rates. Immune-checkpoint blockade and ACT have shown excellent results in other solid tumors, especially in melanoma. Unfortunately, these results have not been extrapolated to GBM. We have developed a novel...

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Publicat a:Neuro Oncol
Autors principals: Ogando-Rivas, Elizabeth, Yang, Changlin, Castillo, Paul, Dechkovskaia, Anjelika, Mitchell, Duane
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846700/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.520
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