TMIC-30. MICROGLIA/BRAIN MACROPHAGES PROMOTE GLIOMA GROWTH BY EXPRESSING GLYCOPROTEIN NMB

BACKGROUND: Glioma-associated microglia and blood-derived macrophages (GAMs) promote tumor growth in experimental mouse glioma models. Using microarray and RNA sequencing, we have previously shown that GAMs upregulate the expression of Glycoprotein NMB/Osteoactivin (GPNMB) when compared to naïve mic...

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Publicado en:Neuro Oncol
Autores principales: Yalcin, Fatih, Buonfiglioli, Alice, Efecan Efe, Ibrahim, Haneke, Hannah, Kuhrt, Leonard D, Synowitz, Michael, Nickl, Bernadette, Bader, Michael, Kettenmann, Helmut, Dzaye, Omar
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Tumor Microenvironment
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846579/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1064
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