TMIC-20. ELIMINATION OF SENESCENT ASTROCYTES IN THE BRAIN TUMOR MICROENVIRONMENT ATTENUATES GLIOBLASTOMA RECURRENCE AFTER RADIOTHERAPY

Glioblastomas (GBM) are treated with high doses of ionizing radiation (IR) yet these tumors inevitably recur, and the recurrent tumors are highly therapy resistant. During GBM therapy, the surrounding brain tissue is irradiated along with the tumor. IR induces senescence in multiple cell types, and...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Fletcher-Sananikone, Eliot, Mukherjee, Bipasha, Burma, Sandeep
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Tumor Microenvironment
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846542/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1054
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