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TMIC-14. PD-L1 EXPRESSION IS NEGATIVELY CORRELATED TO OUTCOMES IN PATIENTS WITH MGMT METHYLATED PROMOTERS IN GBM

BACKGROUND: Glioblastoma is a high-grade glioma and is considered the most aggressive primary brain tumor with a median overall survival of 11–15 months. Methylation of the promoter of the MGMT gene, which encodes a DNA repair protein, has been shown to be a good prognostic indicator for GBM surviva...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Srivastava, Siddhartha, Choi, John, Lim, Michael
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846396/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1048
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