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Comprehensive Analysis of MGMT Promoter Methylation: Correlation with MGMT Expression and Clinical Response in GBM

O(6)-methylguanine DNA-methyltransferase (MGMT) promoter methylation has been identified as a potential prognostic marker for glioblastoma patients. The relationship between the exact site of promoter methylation and its effect on gene silencing, and the patient's subsequent response to therapy...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Shah, Nameeta, Lin, Biaoyang, Sibenaller, Zita, Ryken, Timothy, Lee, Hwahyung, Yoon, Jae-Geun, Rostad, Steven, Foltz, Greg
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017549/
https://ncbi.nlm.nih.gov/pubmed/21249131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016146
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