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The Loss of ARNT/HIF1β in Male Pancreatic β-Cells Is Protective Against High-Fat Diet–Induced Diabetes

The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT)/hypoxia-inducible factor (HIF)-1β (ARNT/HIF1β) plays a key role in maintaining β-cell function and has been shown to be one of the most downregulated transcription factors in islets from patients with type 2 diabetes. We...

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Foilsithe in:Endocrinology
Main Authors: Hoang, Monica, Paglialunga, Sabina, Bombardier, Eric, Tupling, A Russell, Joseph, Jamie W
Formáid: Artigo
Teanga:Inglês
Foilsithe: Endocrine Society 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846328/
https://ncbi.nlm.nih.gov/pubmed/31580427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00936
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