PP4 phosphatase cooperates in recombinational DNA repair by enhancing double-strand break end resection

The role of Rad53 in response to a DNA lesion is central for the accurate orchestration of the DNA damage response. Rad53 activation relies on its phosphorylation by Mec1 and its own autophosphorylation in a manner dependent on the adaptor Rad9. While the mechanism behind Rad53 activation has been w...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Villoria, María Teresa, Gutiérrez-Escribano, Pilar, Alonso-Rodríguez, Esmeralda, Ramos, Facundo, Merino, Eva, Campos, Adrián, Montoya, Alex, Kramer, Holger, Aragón, Luis, Clemente-Blanco, Andrés
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846210/
https://ncbi.nlm.nih.gov/pubmed/31544936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz794
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