TMOD-11. CHARACTERISATION OF THE POST-SURGICAL INVASIVE TUMOUR NICHE USING ASTROCYTE-GLIOBLASTOMA ORGANOIDS AND DECELLULARISED HUMAN BRAIN

Glioblastoma therapeutic challenges are in considerable part due to myriad survival mechanisms which allow malignant cells to repurpose signalling pathways within discreet microenvironments. These Darwinian adaptations facilitate invasion into brain parenchyma and perivascular space. We hypothesised...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Diksin, Mohammed, Rowlinson, Jonathan, Kondrashov, Alexander, Denning, Chris, Hughes, Jaime, Constantin-Teodosiu, Tim, Cui, Wei, Scurr, David, Ahmad, Omar, Gell, Christopher, Onion, David, Croxall, Nicola, Smith, Stuart, Rahman, Ruman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Tumor Models
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846141/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1110
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