Characterisation of the invasive tumour niche using astrocyte-glioblastoma organoids and decellularised human brain

Glioblastoma therapeutic challenges are in considerable part due to myriad survival adaptations and mechanisms, which allow malignant cells to repurpose signalling pathways within discreet microenvironments. These Darwinian adaptations facilitate invasion into brain parenchyma and perivascular space...

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Published in:Neuro Oncol
Main Authors: Diksin, Mohammed, Rowlinson, Jonathan, Kondrashov, Alexandar, Denning, Chris, Hughes, Jamie, Constantin-Teodo, Tim, Cui, Wei, Gell, Chris, Onion, David, Croxall, Nicola, Smith, Stuart, Rahman, Ruman
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790000/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz167.028
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