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Characterisation of the invasive tumour niche using astrocyte-glioblastoma organoids and decellularised human brain

Glioblastoma therapeutic challenges are in considerable part due to myriad survival adaptations and mechanisms, which allow malignant cells to repurpose signalling pathways within discreet microenvironments. These Darwinian adaptations facilitate invasion into brain parenchyma and perivascular space...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Diksin, Mohammed, Rowlinson, Jonathan, Kondrashov, Alexandar, Denning, Chris, Hughes, Jamie, Constantin-Teodo, Tim, Cui, Wei, Gell, Chris, Onion, David, Croxall, Nicola, Smith, Stuart, Rahman, Ruman
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790000/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz167.028
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