TMIC-45. RADIATION THERAPY-INDUCED EPIGENETIC REWIRING PROMOTES GLIOMA PHENOTYPIC PLASTICITY

Therapeutic failure and relapse of glioblastoma (GBM) tumors is attributed to a fraction of chemo- and radiation-resistant glioma stem cells (GSCs). Growing evidence indicates that GSCs and tumor cells elicit phenotypic plasticity in response to radiation-therapy (RT) such as de-differentiation and...

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Publicat a:Neuro Oncol
Autors principals: Deepthi Muthukrishnan, Sree, Wang, Qing, Qin, Yue, Kawaguchi, Riki, Johnson, Maverick, Prasad, Rachna, Condro, Michael, Kornblum, Harley
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Tumor Microenvironment
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845922/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1079
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