OMRT-5. Therapy-induced reprogramming drives glioma vascular transdifferentiation and recurrence

Therapy-resistant glioma cells elicit remarkable phenotypic plasticity leading to aggressive tumor recurrence. Here, we used single-cell and whole transcriptomic sequencing to uncover that radiation treatment induces a dynamic shift in functional states of glioma cells allowing for acquisition of ei...

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Publicado en:Neurooncol Adv
Autores principales: Muthukrishnan, Sree Deepthi, Kawaguchi, Riki, Nair, Pooja, Prasad, Rachna, Qin, Yue, Condro, Michael, Wang, Qing, Alvarado, Alvaro, Kornblum, Harley
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
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Supplement Abstracts
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255432/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.030
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