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INTERACTIONS BETWEEN GENES FROM AGING-RELATED PATHWAYS: IMPACT ON HUMAN LONGEVITY

Role of genetic interactions (GxG) in human longevity remains poorly understood. We hypothesized that GxG between genes from biologically connected pathways involved in aging may impact longevity. To test this hypothesis, we selected 53 candidate genes from the aging-related pathways (IGF-1/AKT/FOXO...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Ukraintseva, Svetlana, Duan, Matt, Wu, Deqing, Arbeev, Konstantin, Kulminski, Alexander, Zmuda, Joseph M, Christensen, Kaare, Yashin, Anatoliy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845781/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.3284
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