INTERACTIONS BETWEEN GENES FROM AGING-RELATED PATHWAYS: IMPACT ON HUMAN LONGEVITY

Role of genetic interactions (GxG) in human longevity remains poorly understood. We hypothesized that GxG between genes from biologically connected pathways involved in aging may impact longevity. To test this hypothesis, we selected 53 candidate genes from the aging-related pathways (IGF-1/AKT/FOXO...

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Bibliografiske detaljer
Udgivet i:Innov Aging
Main Authors: Ukraintseva, Svetlana, Duan, Matt, Wu, Deqing, Arbeev, Konstantin, Kulminski, Alexander, Zmuda, Joseph M, Christensen, Kaare, Yashin, Anatoliy
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Session Lb1545 (Late Breaking Poster)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845781/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.3284
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