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CELLULAR SENESCENCE AS A THERAPEUTIC TARGET FOR GEROSCIENCE-GUIDED CLINICAL TRIALS

The geroscience hypothesis holds that targeting fundamental mechanisms of aging has the potential to prevent or reduce severity of multiple age-related diseases. Cellular senescence is a key mechanism that may be driving disease in human aging, including Idiopathic pulmonary fibrosis (IPF), a progre...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Justice, Jamie N, Nambiar, Anoop M, Tchkonia, Tamar, LeBrasseur, Nathan K, Musi, Nicolas, Kritchevsky, Stephen B, Kirkland, James L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845774/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.2987
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