TMIC-06. MYELOID POPULATIONS AND THE EFFECT OF NEOADJUVANT PD-1 INHIBITION IN THE GLIOBLASTOMA MICROENVIRONMENT: A SURFACEOMIC AND TRANSCRIPTOMIC DISSECTION AT THE SINGLE-CELL LEVEL

INTRODUCTION: Glioblastoma (GBM) is the most common malignant brain tumor in adults and is associated with a dismal prognosis. Neoadjuvant anti-PD-1 blockade has demonstrated efficacy in melanoma, non-small cell lung cancer and recurrent GBM; however, responses vary. While T cells have garnered cons...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Mochizuki, Aaron, Lee, Alexander, Orpilla, Joey, Kienzler, Jenny, Galvez, Mildred, Chow, Frances, Davidson, Tom, Wang, Anthony, Everson, Richard, Liau, Linda, Cloughesy, Timothy, Prins, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Tumor Microenvironment
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845723/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1040
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