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SENESCENCE SECRETOME: BIOMARKERS OF BIOLOGICAL AGING AND POSTOPERATIVE OUTCOMES

Senescent cells drive age-related tissue dysfunction through their potent secretome, termed the senescence associated secretory phenotype (SASP). Circulating concentrations of SASP factors may reflect biological age and serve as clinically useful biomarkers of surgical risk and ultimately, surrogate...

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Dettagli Bibliografici
Pubblicato in:Innov Aging
Autori principali: Schafer, Marissa, Zhang, Xu, Kumar, Amanika, White, Thomas, Atkinson, Elizabeth, Burning, Michelle, LeBrasseur, Nathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845427/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.370
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