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THE LONGEVITY ASSOCIATED ALLELE OF FOXO3 PROTECTS AGAINST TELOMERE ATTRITION DURING AGING

Telomere attrition in proliferative tissues is a hallmark feature of human aging. To date, the genetic influence on the rate of telomere attrition is poorly understood. Previously we discovered a variant of the FOXO3 gene that is strongly associated with human longevity, an observation that has been...

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Bibliographic Details
Published in:Innov Aging
Main Authors: Allsopp, Richard, Davy, Philip, Willcox, Craig, Chen, Randi, Shimabukuro, Michio, de Vivo, Immaculata, Willcox, Bradley J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845095/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.374
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