NOVEL GAMMA-SECRETASE MODULATOR REGULATES APP PROCESSING AND INFLAMMATORY RESPONSES IN NPM-EXPOSED MICE

Air pollution is associated with accelerated cognitive decline and increased risk of dementia in older populations (Cacciottolo et al 2017; Chen et al 2017). Rodent models of air pollution exposure also show Alzheimer-like changes including glial inflammatory responses and increased levels of endoge...

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Bibliografiske detaljer
Udgivet i:Innov Aging
Main Authors: D'Agostino, Carla, Cacciottolo, Mafalda, Sioutas, Constantinos, Wagner, Steven L, Tanzi, Rudolph E, Morgan, Todd E, Finch, Caleb E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Session 825 (Poster)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844916/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.353
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