Verapamil Ameliorates Motor Neuron Degeneration and Improves Lifespan in the SOD1(G93A) Mouse Model of ALS by Enhancing Autophagic Flux

Amyotrophic lateral sclerosis (ALS) is a progressive, paralytic disorder caused by selective degeneration of motor neurons in the brain and spinal cord. Our previous studies indicated that abnormal protein aggregation and dysfunctional autophagic flux might contribute to the disease pathogenesis. In...

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Detalles Bibliográficos
Publicado en:Aging Dis
Main Authors: Zhang, Xiaojie, Chen, Sheng, Lu, Kaili, Wang, Feng, Deng, Jiangshan, Xu, Zhouwei, Wang, Xiuzhe, Zhou, Qinming, Le, Weidong, Zhao, Yuwu
Formato: Artigo
Idioma:Inglês
Publicado: JKL International LLC 2019
Assuntos:
Orginal Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844595/
https://ncbi.nlm.nih.gov/pubmed/31788329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2019.0228
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