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Quantification of tau protein lysine methylation in aging and Alzheimer’s disease

Tau is a microtubule-associated protein that normally interacts in monomeric form with the neuronal cytoskeleton. In Alzheimer’s disease, however, it aggregates to form the structural component of neurofibrillary lesions. The transformation is controlled in part by age- and disease-associated post-t...

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Bibliographische Detailangaben
Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Huseby, Carol J., Hoffman, Claire N., Cooper, Grace L., Cocuron, Jean-Christophe, Alonso, Ana P., Thomas, Stefani N., Yang, Austin J., Kuret, Jeff
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844542/
https://ncbi.nlm.nih.gov/pubmed/31450505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190604
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