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Quantification of tau protein lysine methylation in aging and Alzheimer’s disease

Tau is a microtubule-associated protein that normally interacts in monomeric form with the neuronal cytoskeleton. In Alzheimer’s disease, however, it aggregates to form the structural component of neurofibrillary lesions. The transformation is controlled in part by age- and disease-associated post-t...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Huseby, Carol J., Hoffman, Claire N., Cooper, Grace L., Cocuron, Jean-Christophe, Alonso, Ana P., Thomas, Stefani N., Yang, Austin J., Kuret, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844542/
https://ncbi.nlm.nih.gov/pubmed/31450505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190604
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