FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy

Mitochondrial quality control is essential for maintaining a healthy population of mitochondria. Two proteins associated with Parkinson disease, the kinase PINK1 and the E3 ubiquitin ligase PRKN, play a central role in the selective degradation of heavily damaged mitochondria (mitophagy), thus avoid...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Autophagy
मुख्य लेखकों: Soutar, Marc P. M., Kempthorne, Liam, Annuario, Emily, Luft, Christin, Wray, Selina, Ketteler, Robin, Ludtmann, Marthe H. R., Plun-Favreau, Hélène
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2019
विषय:
Letter to the Editor
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844515/
https://ncbi.nlm.nih.gov/pubmed/31060423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1603549
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