A carregar...
The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab
G309 or S310 mutations on the HER2 extracellular domain II induce receptor activation. Clinically, S310F is most frequent among HER2 extracellular domain mutations and patients with the S310F mutation without HER2 amplification responded to trastuzumab with or without the pertuzumab combination. How...
Na minha lista:
| Publicado no: | Biomolecules |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6843359/ https://ncbi.nlm.nih.gov/pubmed/31635022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9100629 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|