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Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex
Trastuzumab and pertuzumab are monoclonal antibodies that bind to distinct subdomains of the extracellular domain of human epidermal growth factor receptor 2 (HER2). Adding these monoclonal antibodies to the treatment regimen of HER2-positive breast cancer has changed the paradigm for treatment in t...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6493747/ https://ncbi.nlm.nih.gov/pubmed/31042744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216095 |
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