LC-MS-based metabolomics analysis to identify meprin-β-associated changes in kidney tissue from mice with STZ-induced type 1 diabetes and diabetic kidney injury

Meprin metalloproteases have been implicated in the pathophysiology of diabetic kidney disease (DKD). Single-nucleotide polymorphisms in the meprin-β gene have been associated with DKD in Pima Indians, a Native American ethnic group with an extremely high prevalence of DKD. In African American men w...

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Bibliographic Details
Published in:Am J Physiol Renal Physiol
Main Authors: Gooding, Jessica, Cao, Lei, Ahmed, Faihaa, Mwiza, Jean-Marie, Fernander, Mizpha, Whitaker, Courtney, Acuff, Zach, McRitchie, Susan, Sumner, Susan, Ongeri, Elimelda Moige
Format: Artigo
Language:Inglês
Published: American Physiological Society 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843037/
https://ncbi.nlm.nih.gov/pubmed/31411076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00166.2019
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