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Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes

Meprins are membrane-bound and secreted metalloproteinases consisting of α and/or β subunits that are highly expressed in kidney epithelial cells and are differentially expressed in podocytes and leukocytes (macrophages and monocytes). Several studies have implicated meprins in the progression of di...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Bylander, John E., Ahmed, Faihaa, Conley, Sabena M., Mwiza, Jean-Marie, Ongeri, Elimelda Moige
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540529/
https://ncbi.nlm.nih.gov/pubmed/28804725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9035038
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