Antagonism of major histocompatibility complex class II invariant chain peptide during chronic lipopolysaccharide treatment rescues autoregulatory behavior

Toll-like receptor 4 (TLR4) activation contributes to vascular dysfunction in pathological conditions such as hypertension and diabetes, but the role of chronic TLR4 activation on renal autoregulatory behavior is unknown. We hypothesized that subclinical TLR4 stimulation with low-dose lipopolysaccha...

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Publicado en:Am J Physiol Renal Physiol
Main Authors: Van Beusecum, Justin P., Zhang, Shali, Beltran, Estevan, Cook, Anthony K., Tobin, Richard P., Newell-Rogers, M. Karen, Inscho, Edward W.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843034/
https://ncbi.nlm.nih.gov/pubmed/31432707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00164.2019
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