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Acute Toll-like Receptor 4 Activation Impairs Rat Renal Microvascular Autoregulatory Behaviour

AIM: Little is known about how toll-like receptor 4 (TLR4) influences the renal microvasculature. We hypothesized that acute TLR4 stimulation with lipopolysaccharide (LPS) impairs afferent arteriole autoregulatory behaviour, partially through reactive oxygen species (ROS). METHODS: We assessed affer...

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Detalhes bibliográficos
Publicado no:Acta Physiol (Oxf)
Main Authors: Van Beusecum, Justin P., Zhang, Shali, Cook, Anthony K., Inscho, Edward W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641241/
https://ncbi.nlm.nih.gov/pubmed/28544543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12899
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