Tamoxifen-induced, intestinal-specific deletion of Slc5a6 in adult mice leads to spontaneous inflammation: involvement of NF-κB, NLRP3, and gut microbiota

The sodium-dependent multivitamin transporter (SMVT; SLC5A6) is involved in intestinal absorption of vitamin B7 (biotin). We have previously shown that mice with an embryonic intestinal-specific SMVT knockout (KO) develop biotin deficiency and severe spontaneous intestinal inflammation in addition t...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: Sabui, Subrata, Skupsky, Jonathan, Kapadia, Rubina, Cogburn, Kyle, Lambrecht, Nils W., Agrawal, Anshu, Said, Hamid M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842991/
https://ncbi.nlm.nih.gov/pubmed/31369292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00172.2019
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars