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Tamoxifen-induced, intestinal-specific deletion of Slc5a6 in adult mice leads to spontaneous inflammation: involvement of NF-κB, NLRP3, and gut microbiota
The sodium-dependent multivitamin transporter (SMVT; SLC5A6) is involved in intestinal absorption of vitamin B7 (biotin). We have previously shown that mice with an embryonic intestinal-specific SMVT knockout (KO) develop biotin deficiency and severe spontaneous intestinal inflammation in addition t...
שמור ב:
| הוצא לאור ב: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Physiological Society
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6842991/ https://ncbi.nlm.nih.gov/pubmed/31369292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00172.2019 |
| תגים: |
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