Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss

Pancreatic beta-cell death is a major factor in the pathogenesis of type 1 diabetes (T1D), but straightforward methods to measure beta-cell loss in humans are lacking, underlining the need for novel biomarkers. Using studies in INS-1 cells, human islets, diabetic mice, and serum samples of subjects...

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Udgivet i:Am J Physiol Endocrinol Metab
Main Authors: Xu, Guanlan, Thielen, Lance A., Chen, Junqin, Grayson, Truman B., Grimes, Tiffany, Bridges, S. Louis, Tse, Hubert M., Smith, Blair, Patel, Rakesh, Li, Peng, Evans-Molina, Carmella, Ovalle, Fernando, Shalev, Anath
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842918/
https://ncbi.nlm.nih.gov/pubmed/31408375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00122.2019
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