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miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function

Glucagon-like peptide 1 receptor (GLP1R) agonists are widely used to treat diabetes. However, their function is dependent on adequate GLP1R expression, which is downregulated in diabetes. GLP1R is highly expressed on pancreatic β-cells, and activation by endogenous incretin or GLP1R agonists increas...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Jo, SeongHo, Chen, Junqin, Xu, Guanlan, Grayson, Truman B., Thielen, Lance A., Shalev, Anath
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780066/
https://ncbi.nlm.nih.gov/pubmed/29101219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0506
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