Increased pyruvate dehydrogenase activity in skeletal muscle of growth-restricted ovine fetuses

Fetal sheep with placental insufficiency-induced intrauterine growth restriction (IUGR) have lower fractional rates of glucose oxidation and greater gluconeogenesis, indicating lactate shuttling between skeletal muscle and liver. Suppression of pyruvate dehydrogenase (PDH) activity was proposed beca...

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Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Pendleton, Alexander L., Humphreys, Laurel R., Davis, Melissa A., Camacho, Leticia E., Anderson, Miranda J., Limesand, Sean W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842904/
https://ncbi.nlm.nih.gov/pubmed/31314546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00106.2019
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