Increased pyruvate dehydrogenase activity in skeletal muscle of growth-restricted ovine fetuses

Fetal sheep with placental insufficiency-induced intrauterine growth restriction (IUGR) have lower fractional rates of glucose oxidation and greater gluconeogenesis, indicating lactate shuttling between skeletal muscle and liver. Suppression of pyruvate dehydrogenase (PDH) activity was proposed beca...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Pendleton, Alexander L., Humphreys, Laurel R., Davis, Melissa A., Camacho, Leticia E., Anderson, Miranda J., Limesand, Sean W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842904/
https://ncbi.nlm.nih.gov/pubmed/31314546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00106.2019
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