Fra-2 negatively regulates postnatal alveolar septation by modulating myofibroblast function

Mice that globally overexpress the transcription factor Fos-related antigen-2 (Fra-2) develop extensive pulmonary fibrosis and pulmonary vascular remodeling. To determine if these phenotypes are a consequence of ectopic Fra-2 expression in vascular smooth muscle cells and myofibroblasts, we generate...

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Detalles Bibliográficos
Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Tsujino, Kazuyuki, Li, John T., Tsukui, Tatsuya, Ren, Xin, Bakiri, Latifa, Wagner, Erwin, Sheppard, Dean
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842869/
https://ncbi.nlm.nih.gov/pubmed/28818870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00062.2017
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