Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency

BACKGROUND: Lipopolysaccharide-responsive beige-like anchor (LRBA) deficiency presents with susceptibility to infections, autoimmunity and lymphoproliferation. The long-term efficacy of CTLA4-Ig (abatacept) as targeted therapy for its immune dysregulatory features remains to be established. OBJECTIV...

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Publicado en:J Allergy Clin Immunol Pract
Main Authors: Kiykim, Ayca, Ogulur, Ismail, Dursun, Esra, Charbonnier, Louis Marie, Nain, Ercan, Cekic, Sukru, Dogruel, Dilek, Karaca, Neslihan Edeer, Cogurlu, Mujde Tuba, Bilir, Ozlem Arman, Cansever, Murat, Kapakli, Hasan, Baser, Dilek, Kasap, Nurhan, Kutlug, Seyhan, Altintas, Derya Ufuk, Al-Shaibi, Ahmad, Agrebi, Nourhen, Kara, Manolya, Guven, Ayla, Somer, Ayper, Aydogmus, Cigdem, Ayaz, Nuray Aktay, Metin, Ayse, Aydogan, Metin, Uncuoglu, Aysen, Patiroglu, Turkan, Yildiran, Alisan, Guner, Sukru Nail, Keles, Sevgi, Reisli, Ismail, Aksu, Guzide, Kutukculer, Necil, Kilic, Sara S., Yilmaz, Mustafa, Karakoc-Aydiner, Elif, Lo, Bernice, Ozen, Ahmet, Chatila, Talal A., Baris, Safa
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842687/
https://ncbi.nlm.nih.gov/pubmed/31238161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaip.2019.06.011
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