Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency

BACKGROUND: Lipopolysaccharide-responsive beige-like anchor (LRBA) deficiency presents with susceptibility to infections, autoimmunity and lymphoproliferation. The long-term efficacy of CTLA4-Ig (abatacept) as targeted therapy for its immune dysregulatory features remains to be established. OBJECTIV...

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Bibliografiske detaljer
Udgivet i:J Allergy Clin Immunol Pract
Main Authors: Kiykim, Ayca, Ogulur, Ismail, Dursun, Esra, Charbonnier, Louis Marie, Nain, Ercan, Cekic, Sukru, Dogruel, Dilek, Karaca, Neslihan Edeer, Cogurlu, Mujde Tuba, Bilir, Ozlem Arman, Cansever, Murat, Kapakli, Hasan, Baser, Dilek, Kasap, Nurhan, Kutlug, Seyhan, Altintas, Derya Ufuk, Al-Shaibi, Ahmad, Agrebi, Nourhen, Kara, Manolya, Guven, Ayla, Somer, Ayper, Aydogmus, Cigdem, Ayaz, Nuray Aktay, Metin, Ayse, Aydogan, Metin, Uncuoglu, Aysen, Patiroglu, Turkan, Yildiran, Alisan, Guner, Sukru Nail, Keles, Sevgi, Reisli, Ismail, Aksu, Guzide, Kutukculer, Necil, Kilic, Sara S., Yilmaz, Mustafa, Karakoc-Aydiner, Elif, Lo, Bernice, Ozen, Ahmet, Chatila, Talal A., Baris, Safa
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842687/
https://ncbi.nlm.nih.gov/pubmed/31238161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaip.2019.06.011
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