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Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch

The reactivation of quiescent cells to proliferate is fundamental to tissue repair and homeostasis in the body. Often referred to as the G0 state, quiescence is, however, not a uniform state but with graded depth. Shallow quiescent cells exhibit a higher tendency to revert to proliferation than deep...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Fujimaki, Kotaro, Li, Ruoyan, Chen, Hengyu, Della Croce, Kimiko, Zhang, Hao Helen, Xing, Jianhua, Bai, Fan, Yao, Guang
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842626/
https://ncbi.nlm.nih.gov/pubmed/31636214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915905116
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