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Crack the state of silence: Tune the depth of cellular quiescence for cancer therapy

The regulation of cellular quiescence underlies numerous physiopathological phenomena. We recently found that quiescence depth can be tuned as to adjust a dimmer switch, by altering the expression of genes in the Retinoblastoma (Rb)-E2f pathway. Reducing quiescence depth may wake dormant cancer cell...

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Publicat a:Mol Cell Oncol
Autors principals: Fujimaki, Kotaro, Yao, Guang
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791855/
https://ncbi.nlm.nih.gov/pubmed/29404395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1403531
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