Structure-function analysis of β-arrestin Kurtz reveals a critical role of receptor interactions in downregulation of GPCR signaling in vivo

Arrestins control signaling via the G protein coupled receptors (GPCRs), serving as both signal terminators and transducers. Previous studies identified several structural elements in arrestins that contribute to their functions as GPCR regulators. However, the importance of these elements in vivo i...

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Vydáno v:Dev Biol
Hlavní autoři: Chai, Fei, Xu, Wenjian, Musoke, Timothy, Tarabelsi, George, Assaad, Steven, Freedman, Jason, Peterson, Rachel, Piotrowska, Katarzyna, Byrnes, Jarrett, Rogers, Stephen, Veraksa, Alexey
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842422/
https://ncbi.nlm.nih.gov/pubmed/31325455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.07.013
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