Structure-function analysis of β-arrestin Kurtz reveals a critical role of receptor interactions in downregulation of GPCR signaling in vivo

Arrestins control signaling via the G protein coupled receptors (GPCRs), serving as both signal terminators and transducers. Previous studies identified several structural elements in arrestins that contribute to their functions as GPCR regulators. However, the importance of these elements in vivo i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Dev Biol
Päätekijät: Chai, Fei, Xu, Wenjian, Musoke, Timothy, Tarabelsi, George, Assaad, Steven, Freedman, Jason, Peterson, Rachel, Piotrowska, Katarzyna, Byrnes, Jarrett, Rogers, Stephen, Veraksa, Alexey
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842422/
https://ncbi.nlm.nih.gov/pubmed/31325455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.07.013
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