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In vivo immunogenicity assessment and vaccine efficacy evaluation of a chimeric tandem repeat of epitopic region of OMP31 antigen fused to interleukin 2 (IL-2) against Brucella melitensis in BALB/c mice

BACKGROUND: Designing a potent recombinant vaccine, using the appropriate subunits with the greatest effect on stimulating the immune system, especially in the case of intracellular pathogens such as gram negative Brucella Melitensis bacteria, is of great importance. In this study, three repeats of...

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Bibliografische gegevens
Gepubliceerd in:BMC Vet Res
Hoofdauteurs: Nazifi, Narges, Tahmoorespur, Mojtaba, Sekhavati, Mohammad Hadi, Haghparast, Alireza, Behroozikhah, Ali Mohammad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842255/
https://ncbi.nlm.nih.gov/pubmed/31703683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-2074-7
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