In vivo immunogenicity assessment and vaccine efficacy evaluation of a chimeric tandem repeat of epitopic region of OMP31 antigen fused to interleukin 2 (IL-2) against Brucella melitensis in BALB/c mice

BACKGROUND: Designing a potent recombinant vaccine, using the appropriate subunits with the greatest effect on stimulating the immune system, especially in the case of intracellular pathogens such as gram negative Brucella Melitensis bacteria, is of great importance. In this study, three repeats of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Vet Res
Main Authors: Nazifi, Narges, Tahmoorespur, Mojtaba, Sekhavati, Mohammad Hadi, Haghparast, Alireza, Behroozikhah, Ali Mohammad
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842255/
https://ncbi.nlm.nih.gov/pubmed/31703683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-2074-7
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