In vivo immunogenicity assessment and vaccine efficacy evaluation of a chimeric tandem repeat of epitopic region of OMP31 antigen fused to interleukin 2 (IL-2) against Brucella melitensis in BALB/c mice

BACKGROUND: Designing a potent recombinant vaccine, using the appropriate subunits with the greatest effect on stimulating the immune system, especially in the case of intracellular pathogens such as gram negative Brucella Melitensis bacteria, is of great importance. In this study, three repeats of...

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Detalles Bibliográficos
Publicado en:BMC Vet Res
Main Authors: Nazifi, Narges, Tahmoorespur, Mojtaba, Sekhavati, Mohammad Hadi, Haghparast, Alireza, Behroozikhah, Ali Mohammad
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842255/
https://ncbi.nlm.nih.gov/pubmed/31703683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-2074-7
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